Food Allergy Market to Rise by 2034 | Aimmune Therapeutics, Inc., Novartis Pharmaceuticals, DBV Technologies, InnoUp Farma S.L., COUR Pharmaceutical Development Company Inc., Vedanta Biosciences, Inc., Regeneron Pharmaceuticals, Genentech, and others

DelveInsight's "Food Allergy Market Insights, Epidemiology, and Market Forecast-2034" report delivers an in-depth understanding of Food Allergy, historical and forecasted epidemiology as well as the Food Allergy market trends in the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom), and Japan.

The Food Allergy market report provides current treatment practices, emerging drugs, the market share of the individual therapies, and the current and forecasted Food Allergy market size from 2020 to 2034, segmented by seven major markets. The Report also covers current Food Allergy treatment practice/algorithm, market drivers, market barriers, and unmet medical needs to curate the best opportunities and assesses the underlying potential of the Food Allergy market.

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Key highlights from the food allergy market report:
The food allergy market was valued at USD 1,648 million in 2023, with DelveInsight's analysis indicating growth driven by increased awareness and the introduction of new therapies. By the end of 2034, the market is expected to expand significantly at a strong CAGR during the forecast period (2024-2034).

In the seven major markets (7MM), the United States led in 2023, capturing nearly 86% of the total market share. The EU4 countries and the UK accounted for approximately USD 167 million, with anticipated robust growth in the coming years. Among European nations, Spain held the largest market share in 2023, followed by Italy, Germany, and France, while the UK had the smallest share.

DelveInsight's analysis reveals that about 58% of all food allergy cases in the 7MM were in the United States. In 2023, the EU4 and the UK together reported approximately 16.9 million food allergy cases.

The market includes key categories such as epinephrine, antihistamines, steroids, beta-2-agonists, and Palforzia, with Palforzia generating the highest revenue at around USD 720 million in 2023. The overall food allergy treatment market is projected to grow during the forecast period, driven by the emergence of new and effective therapies, including Ligelizumab (QGE031), Viaskin Peanut, and Omalizumab, among others.

Food Allergy Overview
Food allergies occur when the immune system mistakenly identifies certain proteins in food as harmful, leading to an allergic reaction. These reactions can vary in severity and may even be life-threatening in some cases.

Causes
Food allergies can develop due to:

Genetic Predisposition: A family history of allergies can increase the risk.
Environmental Factors: Exposure to certain foods at a young age or changes in diet may influence allergy development.
Immune System Responses: The immune system's abnormal response to specific food proteins triggers allergies.
Common food allergens include:

Peanuts
Tree nuts
Milk
Eggs
Wheat
Soy
Fish
Shellfish
Signs and Symptoms
Symptoms of food allergies can range from mild to severe and may include:

Skin Reactions: Hives, eczema, or redness
Gastrointestinal Symptoms: Nausea, vomiting, diarrhea, or stomach cramps
Respiratory Issues: Nasal congestion, sneezing, difficulty breathing, or wheezing
Anaphylaxis: A severe, life-threatening reaction that can include swelling of the throat, rapid pulse, dizziness, or loss of consciousness
Diagnosis
Diagnosing a food allergy typically involves:

Medical History: Discussing symptoms and family history with a healthcare provider.
Physical Examination: Assessing skin and overall health.
Allergy Testing:
Skin Prick Test: Small amounts of allergens are introduced into the skin to check for reactions.
Blood Tests: Measuring specific antibodies (IgE) to allergens.
Oral Food Challenge: Under medical supervision, consuming suspected allergens to observe reactions.
Treatment Options
Treatment for food allergies primarily focuses on avoiding allergens and managing symptoms:

Avoidance: The most effective strategy is to avoid foods that trigger allergic reactions.
Medications:
Antihistamines: To relieve mild symptoms like itching or hives.
Epinephrine: An injection used for severe reactions (anaphylaxis).
Corticosteroids: To reduce inflammation in more severe cases.
Immunotherapy: Ongoing research is exploring options like oral immunotherapy, which involves gradually introducing small amounts of an allergen to desensitize the immune system.
Food allergies can significantly impact daily life and health. Recognizing symptoms and seeking timely diagnosis and treatment is crucial for managing these allergies effectively. If you suspect you have a food allergy, consult a healthcare professional for personalized advice and care.

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Food Allergy Market

Food allergy treatment encompasses a variety of classifications within the disease landscape. Management primarily relies on the use of epinephrine, antihistamines, steroids, beta-2-agonists, and Palforzia as needed.

Palforzia currently serves as the main revenue generator in the treatment market.

The food allergy market is poised for positive growth with the potential approval of new drugs like Ligelizumab (QGE031), Viaskin Peanut, and Omalizumab, among others.

In 2023, the total market size for food allergy in the seven major markets (7MM) reached approximately USD 1,648 million, with significant growth expected during the forecast period. The United States led the market, accounting for nearly 86% of the total share.

In the same year, the EU4 and the UK together captured an estimated USD 167 million, with projections indicating substantial growth at a high CAGR. Among European countries, Spain held the largest market share, followed by Italy, Germany, and France, while the UK had the smallest share.

Japan represented approximately 4% of the total food allergy market in 2023, with expectations for considerable growth during the study period. Overall, the food allergy treatment market is expected to expand due to the introduction of new and effective therapies.

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Food Allergy Epidemiology

DelveInsight analysts estimate that there were approximately 57.5 million prevalent cases of food allergy in 2023 across the seven major markets (7MM). The United States reported the highest diagnosed prevalence, with around 33.1 million cases. This number is expected to rise during the forecast period due to increased awareness among patients and the introduction of new therapies.

In the EU4 countries and the UK, there were approximately 16.9 million prevalent cases of food allergy in 2023. Significant increases in cases are anticipated across all contributing countries, except Germany, where a decrease is expected. Among the EU4 nations, Spain had the highest proportion of food allergy cases, while the UK reported the fewest.

In Japan, the total prevalent cases of food allergy were estimated at around 7.4 million in 2023, with projections indicating a decrease by 2034.

In the US, food allergy cases were categorized by specific allergens, including cow's milk, peanuts, eggs, wheat, tree nuts, fish, shellfish, soy, and others. Shellfish was the most prevalent allergen, accounting for approximately 8 million cases in 2023.

DelveInsight's analysis also categorized food allergy cases by age, revealing that adults accounted for a higher number of cases (around 28 million) compared to children in the US in 2023.

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Food Allergy Marketed Drugs

Palforzia: Aimmune Therapeutics, Inc.

Approved in 2020, Palforzia is a complex biologic drug used with a structured dosing approach that builds on a century of oral immunotherapy (OIT) research. With OIT, the specific allergenic proteins are ingested initially in very small quantities, followed by incrementally increasing amounts, resulting in the ability to mitigate allergic reactions to the allergen over time. Palforiza is the first approved treatment for patients with peanut allergy. It is oral immunotherapy indicated to mitigate allergic reactions, including anaphylaxis that may occur with accidental exposure to peanuts. Palforzia is approved for use in patients with a confirmed diagnosis of peanut allergy.

Food Allergy Emerging Drugs

Ligelizumab: Novartis Pharmaceuticals

Ligelizumab (QGE031), a humanized anti-IgE antibody developed by Novartis, is a next-generation monoclonal anti-immunoglobulin E (IgE) antibody. It is also directed against Cε3, but is designed to achieve improved IgE suppression, with an equilibrium dissociation constant (KD) of 139 pM (as compared to the KD of omalizumab, ~6-8 nm). Ligelizumab's mechanism of action involves blocking the IgE/FcεRI pathway, a key driver of the inflammatory process in CSU (chronic spontaneous urticaria), and binding with high affinity to the Cε3 domain of IgE.

Viaskin Peanut: DBV Technologies

Viaskin Peanut is the first epicutaneous immunotherapy (EPIT) in development that leverages the skin to activate the immune system and induce desensitization in peanut-allergic children. EPIT aims to target specific epidermal dendritic cells, called Langerhans cells. Pre-clinical research has shown that these cells capture antigens and migrate to the lymph node in order to activate the immune system. By delivering the allergen directly to the lymph node through the Langerhans cells, pre-clinical research has shown that EPIT activates specific regulatory T cells (Tregs) that can down-regulate the Th2-oriented reaction to the allergen.


Food Allergy Pipeline Development Activities

The Food Allergy report provides insights into different therapeutic candidates in Phase II, and Phase III stages. It also analyses Food Allergy key players involved in developing targeted therapeutics.

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Food Allergy Therapeutics Assessment

Major players such as Aimmune Therapeutics, Inc., Novartis Pharmaceuticals, DBV Technologies, InnoUp Farma S.L., COUR Pharmaceutical Development Company Inc., Vedanta Biosciences, Inc., Regeneron Pharmaceuticals, Genentech, and others are assessed as potential therapies to be available in the market in the coming future.

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Food Allergy Report Key Insights

1. Food Allergy Patient Population
2. Food Allergy Market Size and Trends
3. Key Cross Competition in the Food Allergy Market
4. Food Allergy Market Dynamics (Key Drivers and Barriers)
5. Food Allergy Market Opportunities
6. Food Allergy Therapeutic Approaches
7. Food Allergy Pipeline Analysis
8. Food Allergy Current Treatment Practices/Algorithm
9. Impact of Emerging Therapies on the Food Allergy Market

Table of Contents

1. Key Insights
2. Executive Summary
3. Food Allergy Competitive Intelligence Analysis
4. Food Allergy Market Overview at a Glance
5. Food Allergy Disease Background and Overview
6. Food Allergy Patient Journey
7. Food Allergy Epidemiology and Patient Population
8. Food Allergy Treatment Algorithm, Current Treatment, and Medical Practices
9. Food Allergy Unmet Needs
10. Key Endpoints of Food Allergy Treatment
11. Food Allergy Marketed Products
12. Food Allergy Emerging Therapies
13. Food Allergy Seven Major Market Analysis
14. Attribute Analysis
15. Food Allergy Market Outlook (7 major markets)
16. Food Allergy Access and Reimbursement Overview
17. KOL Views on the Food Allergy Market
18. Food Allergy Market Drivers
19. Food Allergy Market Barriers
20. Appendix
21. DelveInsight Capabilities
22. Disclaimer

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