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Press Releases from Ludwig Boltzmann Institute for Cancer Research (1 total)

New strategy to target transcription factor STAT5 to combat leukaemia

Acute myeloid leukaemia (AML) is the most common type of acute cancer of the blood and bone marrow in adults. This type of cancer usually progresses quickly and only 26 percent of the patients survive longer than 5 years as resistance against established treatments arises. The most common molecular cause is FLT3 mutations, which result in hyper-activation of STAT5. An international consortium of researchers now report on an early preclinical

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