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Scalable and pH stable: New C8 and C18 hybrid phases

01-15-2010 02:49 PM CET | Science & Education

Press release from: YMC Europe GmbH

YMC-Triart

YMC-Triart

YMC is introducing a new concept in hybrid stationary phases named YMC Triart for C8 and C18 preparative scale materials. This multilayered hybrid particle succeeds where even modern materials often fail. With a careful balance between hydrophobicity and silanol activity, the new material performs similar to standard ODS or C8 materials. At the same time, it is stable at high pH even at elevated temperatures! Not only does this widen the applicable pH range for the mobile phase usable. Most importantly, it significantly increases the durability of the material during cleaning in place (CIP) cycles. Owing to the selectivity being very similar to existing ODS and C8 phases it can be possible to substitute current material in existing processes with only little adaptation of the process parameters. Such a step can increase productivity tremendously because of longer runtimes and less downtimes due to column repacking.

For new processes the full scalability from analytical to preparative scale is an important advantage. The 3 μm, 5 μm, 10 μm and 15 μm particles are all produced by the same process adapted from FRT (flow reaction technology). This new technology warrants full scalability from analytical to preparative level and improves lot to lot reproducibility even further. True to YMC’s maxim “Same selectivity, day after day, year after year”.

Triart multilayered hybrid stationary phases are available in C8 and C18 modifications. Particle sizes for bulk material are 10 and 15 μm with pore sizes of 12 and 20 nm. Additional materials based to client specification are available upon request.

We are very happy to discuss with you, the advantages Triart could hold for you. For more information or to apply for a test column, please contact your local YMC distributor or YMC Europe directly in Germany.

From headquarters located in Kyoto, Japan, YMC has gradually and consistently matured to a level of international recognition, specifically within the pharmaceutical and biotech world, as one of the leading suppliers of analytical and process-scale silica-based stationary phases for High Performance Liquid Chromatography, preparative equipment, custom purification and method development.
New: Micro Reactor / Flow Chemistry scalable to production scale!
Qualified technical support and backup is available through operations in Japan, the United States (for the "Americas"), India, China and Germany (for Europe, Africa and the Middle East). www.ymc.de

YMC Europe GmbH
Daniel Kune
Schöttmannshof 19
46539 Dinslaken
Germany

Tel.: +49 (0)2064-427 270
E-Mail: kune@ymc.de
www.ymc.de

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