Chronic Rhinosinusitis Without Nasal Polyps Market Size is Set for Rapid Growth as Innovative Treatments and Rising Awareness Drive Demand by 2034

The Chronic Rhinosinusitis Without Nasal Polyps market size is expected to increase during the forecast period with the increasing prevalence, disease awareness, and promising emerging treatment options by leading companies such as Insmed Incorporated, Gossamer Bio, Optinose US Inc., Chia Tai Tianqing Pharmaceutical Group Co., Ltd., Pfizer, Optinose US Inc., Sanofi

[Nevada, United States] - DelveInsight's "Chronic Rhinosinusitis Without Nasal Polyps Market Insights, Epidemiology, and Market Forecast 2034." report offers a detailed examination of Chronic Rhinosinusitis Without Nasal Polyps, covering historical and predicted epidemiology, market trends, and treatment scenarios in the United States, EU4 (Germany, Spain, Italy, France), the United Kingdom, and Japan.

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Key Findings from the Chronic Rhinosinusitis Without Nasal Polyps Market Report:
• The Chronic Rhinosinusitis Without Nasal Polyps market size is poised for significant growth, with an anticipated Compound Annual Growth Rate (CAGR) during the study period (2020-2034).
• In October, 2024: Insmed Incorporated announced that the purpose of their study is to evaluate the efficacy of brensocatib at 10 and 40 milligrams (mg) once daily (QD) compared with placebo in improving clinical symptoms of CRSsNP.
• In July, 2024: Chia Tai Tianqing Pharmaceutical Group Co., Ltd. announced a multicenter, randomized, continuing, Phase II expansion trial to evaluate the safety, efficacy, and immunogenicity of two doses of TQH2722 in the long-term treatment of severe chronic sinusitis with or without nasal polyps.
• In June, 2024: Pfizer announced that the purpose of their study is to compare the efficacy and safety of rimegepant versus placebo in the acute treatment of chronic rhinosinusitis (CRS) with and without nasal polyps. A Phase 2/3, Double-Blind, Randomized, Placebo-Controlled, Safety and Efficacy Trial of BHV-3000 (Rimegepant) Orally Disintegrating Tablet (ODT) for the Acute Treatment of Chronic Rhinosinusitis (CRS) With or Without Nasal Polyps
• In June, 2024: Chia Tai Tianqing Pharmaceutical Group Nanjing Shunxin Pharmaceutical Co., Ltd. announced a Multicenter, Randomized, Double-blind, Placebo-controlled Phase II Clinical Trials to Assess the Effectiveness, Safety and Pharmacokinetics of TQH2722 Injection in Patients With Chronic Sinusitis With or Without Nasal Polyps.
• According to DelveInsight's analysis, the United States accounted for 31,304,322 prevalent cases of CRS in 2022 equivalent to about 45% of the total CRS prevalent cases in the 7MM. On the same lines, the United Statesaccounted for 8,765,210 diagnosed prevalent cases of CRS in 2022 which is expected to increase by 2032 at asignificant CAGR.
• Chronic rhinosinusitis (CRS) is a common condition globally, affecting approximately 10-12% of the adult population, and CRSsNP constitutes the majority of CRS cases, with 60-70% of patients diagnosed with this subtype.
• CRSsNP is frequently associated with conditions such as asthma, allergic rhinitis, and gastroesophageal reflux disease (GERD). The overlap between CRSsNP and these conditions points to shared inflammatory pathways, making treatment more complex for individuals with multiple respiratory issues.
• Key Chronic Rhinosinusitis Without Nasal Polyps Companies are as follows: Insmed Incorporated, Gossamer Bio, Optinose US Inc., Chia Tai Tianqing Pharmaceutical Group Co., Ltd., Pfizer, Optinose US Inc., Sanofi
• Key Chronic Rhinosinusitis Without Nasal Polyps Therapies are as follow: XHANCE (fluticasone propionate), LYR-210, LYR-220, Brensocatib, GB001, Fluticasone Propionate, rimegepant, OPN-375, Dupilumab SAR231893
• Launching multiple stage Chronic Rhinosinusitis Without Nasal Polyps pipeline products is expected to revolutionize market dynamics, further propelling market growth.

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Chronic Rhinosinusitis Without Nasal Polyps Overview:
The Chronic Rhinosinusitis Without Nasal Polyps market is a disease, in which both genetic and environmental factors contribute to its pathogenesis. Chronicrhinosinusitis in adults in most guidelines is characterized by at least 8-12 weeks of at least two symptoms, likenasal blockage/obstruction/congestion, nasal discharge (anterior/posterior nasal drip), facial pain/pressure,and/or reduction or loss of smell and either endoscopic signs of disease or relevant CT scan changes.

Chronic Rhinosinusitis Without Nasal Polyps Epidemiology Segmentation:
The Chronic Rhinosinusitis Without Nasal Polyps market report proffers epidemiological analysis for the study period 2020-2034 in the 7MM segmented into:
• Chronic Rhinosinusitis Without Nasal Polyps Total Prevalent cases
• Chronic Rhinosinusitis Without Nasal Polyps Diagnosed Prevalent Cases
• Chronic Rhinosinusitis Without Nasal Polyps Diagnosed Prevalent Cases
• Chronic Rhinosinusitis Without Nasal Polyps Gender-specific Diagnosed Prevalent Cases

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Chronic Rhinosinusitis Without Nasal Polyps Market Insights
The treatment landscape of chronic rhinitis is limited to minimum or no cure for the indication. The treatmentguidelines are often focused on symptomatic relief. Where, Nucala (mepolizumab, GSK and Dupixent (dupilumab,Sanofi) have been approved for severe Chronic Rhinosinusitis with nasal polyposis, the market for severe ChronicRhinosinusitis without Chronic Rhinosinusitis without Nasal Polyps is dominated by generic such as corticosteroids,antihistamines, and antibiotics. The indication is further managed by the process of Balloon Sinuplasty (RELIEVASPINPLUS).

• ANTIBIOTICS
• Steroids
• Endoscopic sinus surgery

Chronic Rhinosinusitis Without Nasal Polyps Drugs Uptake
• LYR-210: LYR-210 is an investigational product candidate for use in chronic rhinosinusitis (CRS) patients who have failed current treatments and require further intervention. LYR-210 is a bioresorbable nasal implant administered in a brief in-office procedure.
• XHANCE: XHANCE is a drug-device combination product that uses the Exhalation Delivery System (also referred to as the EDS designed to deliver a topical anti inflammatory to the high and deep regions of the nasal cavity where sinuses ventilate and drain.
• Brensocatib is an oral, selective, reversible inhibitor of dipeptidyl peptidase-1 (DPP-1), responsible for activating neutrophil serine proteases (NSPs) including neutrophil elastase (NE), proteinase 3 (PR3), and cathepsin G (CatG). The company is investigating this molecule in patients with CRSsNP.

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Chronic Rhinosinusitis Without Nasal Polyps Therapies and Key Companies:
• XHANCE (fluticasone propionate): Optinose US Inc.
• LYR-210, LYR-220: Lyra Therapeutics
• Brensocatib: Insmed Incorporated
• GB001: Gossamer Bio
• Fluticasone Propionate: Optinose US Inc.
• rimegepant: Pfizer
• OPN-375: Optinose US Inc.
• Dupilumab SAR231893: Sanofi

Chronic Rhinosinusitis Without Nasal Polyps Epidemiology:
Chronic rhinosinusitis (CRS) is a common condition globally, affecting approximately 10-12% of the adult population, and CRSsNP constitutes the majority of CRS cases, with 60-70% of patients diagnosed with this subtype. The prevalence of CRSsNP tends to be higher in regions with significant pollution, allergens, and dry climates. For example, the condition is more prevalent in urban areas where air pollution levels are high compared to rural areas.

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Chronic Rhinosinusitis Without Nasal Polyps Market Drivers:
• Rising Prevalence of Respiratory Conditions
• Advancements in Diagnostic Tools
• Increased Awareness and Demand for Treatment
• Growing Healthcare Expenditure and Access to Care

Chronic Rhinosinusitis Without Nasal Polyps Market Barriers:
• High Cost of Advanced Therapies
• Side Effects of Long-Term Treatment
• Limited Efficacy of Standard Treatments
• Slow Adoption of Innovative Therapies

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Scope of the Chronic Rhinosinusitis Without Nasal Polyps Market Report:
• Study Period: 2020-2034
• Coverage: 7MM (The United States, EU5, and Japan)
• Key Chronic Rhinosinusitis Without Nasal Polyps Companies: Insmed Incorporated, Gossamer Bio, Optinose US Inc., Chia Tai Tianqing Pharmaceutical Group Co., Ltd., Pfizer, Optinose US Inc., Sanofi
• Key Chronic Rhinosinusitis Without Nasal Polyps Therapies: XHANCE (fluticasone propionate), LYR-210, LYR-220, Brensocatib, GB001, Fluticasone Propionate, rimegepant, OPN-375, Dupilumab SAR231893
• Chronic Rhinosinusitis Without Nasal Polyps Therapeutic Assessment: Current marketed and emerging therapies
• Chronic Rhinosinusitis Without Nasal Polyps Market Dynamics: Chronic Rhinosinusitis Without Nasal Polyps Market drivers and Chronic Rhinosinusitis Without Nasal Polyps barriers
• Competitive Intelligence Analysis: SWOT analysis, PESTLE analysis, Porter's five forces, BCG Matrix, Market entry strategies
• Chronic Rhinosinusitis Without Nasal Polyps Unmet Needs: Insights into unmet needs, KOL's views, Analyst's views, Market Access, and Reimbursement.

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Table of Content:

1. Key Insights
2. Report Introduction
3. Country-wise Chronic Rhinosinusitis Without Nasal Polyps (CRSsNP) Market Overview at a Glance
4. Chronic Rhinosinusitis Without Nasal Polyps (CRSsNP) Market Overview by Therapies
5. Methodology of Chronic Rhinosinusitis Without Nasal Polyps Epidemiology and Market
6. Executive Summary of Chronic Rhinosinusitis Without Nasal Polyps (CRSsNP)
7. Key Events
8. Disease Background and Overview: CRSsNP
9. Epidemiology and Patient Population
10. Patient Journey
11. Emerging Drugs
12. CRSsNP: Market Analysis
13. Key Opinion Leaders' Views
14. SWOT Analysis
15. Unmet Needs
16. Market Access and Reimbursement
16.3.1. MHLW
17. Appendix
18. Report Methodology
19. DelveInsight Capabilities
20. Disclaimer

About DelveInsight:
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