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mRNA Extraction and Purification Market Overview: Current Landscape and Future Outlook
According to company's newest research, the Global mRNA Extraction and Purification Market is predicted to record a promising CAGR of 19.2% between 2024 and 2031.
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Numerous downstream experiments require high-quality RNA molecules, including cloning, reverse transcription for cDNA synthesis, RT-PCR, RT-qPCR, and RNA-seq. Methods for purifying RNA comprise phenol-chloroform extraction, spin-column purification, and magnetic particles. Among these, the magnetic particle method for extracting specific mRNA is prevalent.
The particles utilize the poly-A tail that distinguishes mRNA from other RNA. This is particularly beneficial for determining it from rRNA, which is significantly more abundant. Extraction and purification procedures utilize numerous reagents, such as enzymes and buffers containing chaotropic agents, such as guanidinium isothiocyanate, sodium dodecyl sulphate (SDS), Sarcosyl, guanidinium chloride, urea, phenol, or chloroform. Researchers use mRNA to ascertain which proteins are being translated and how much transcript the cell is producing. Synthetic mRNA production requires a purification phase to isolate the final mRNA product from the transcription solution.
Due to the rapid spread of the coronavirus over the past two years, the demand for diagnostic instruments and other devices for critical care has increased dramatically. Rapid COVID-19 infection diagnostics bolsters global drug development and testing facilities. Pharmaceutical growth accelerates research to create ground-breaking molecules to satisfy the expanding demands of drug development. The government provides institutes and laboratories with capital investments for research and development activities to enhance growth prospects. The drug developers' preference for mRNA-based cancer treatments is reflected in the market valuation of mRNA therapeutics. This initiates RNA extraction and purification services and nucleic acid research. Increasing funding initiatives for biotechnology research, significant life sciences research, a growing patient population, and supporting government activities are among the factors driving the market growth.
RNA isolation & purification packages and automated instruments are more expensive than conventional methods, which may hinder market expansion. These costly instruments are unaffordable to institutes and companies with smaller R&D expenditures.
The market for mRNA Extraction and Purification is anticipated to be dominated by North America during the forecast period, owing to the region's high R&D activities and the presence of key market participants. Their product offerings are continually adapted to the market.
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Some major players in the market are Qiagen, Thermo Fisher Scientific, Promega Corporation, Agilent Technologies, Inc, Merck Kgaa, Miltenyi Biotec, Biobasic Inc, Takara Bio, Inc, New England Biolabs, Omega Bio-Tek, Inc, Norgen Biotek, Zymo Research, F. Hoffmann-La Roche Ag, Genaxxon Bioscience Gmbh, Biovision, Analytik Jena Ag, Bio-Rad Laboratories, Inc, AccuBioMed.
Key Developments in the market
• In Jan 2022, Merck KGaA Acquired CDMO Exelead for approximately $780 million in cash. Merck KGaA's LNP and mRNA capabilities will be enhanced due to the agreement. Merck plans to continue investing in mRNA as a modality and will scale up this technology at Exelead's facility. The company now provides comprehensive end-to-end services across the mRNA value chain.
• In Apr 2021, Promega Opened New Research & Development Facility' Kornberg Center' Supporting Science at the Edge of Innovation. This will aid in developing core products and technologies in life science research, cellular and molecular biology, genetic identity, clinical diagnostic and scientific applications, and training.
• In Apr 2020, Thermo Fisher Scientific, Inc. and Hamilton Company collaborated to create an automated nucleic acid extraction platform for forensic laboratories. The ID NIMBUS Presto assay allows for automated DNA extraction from crime scene samples.
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Global mRNA Extraction and Purification Market, by Product, 2024-2031 (Value US$ Mn)
• Kits/Reagents
• Instruments
Global mRNA Extraction and Purification Market, by Application, 2024-2031 (Value US$ Mn)
• Infectious Disease Vaccines
• Other Vaccines
• Therapeutics and Others
Global mRNA Extraction and Purification Market, by End-Users, 2024-2031 (Value US$ Mn)
• Academics and Research Institutes
• Pharmaceutical & Biotechnology Companies
• Contract Research Organizations
• Other End Users (Hospitals, etc)
Global mRNA Extraction and Purification Market, by Region, 2024-2031 (Value US$ Mn)
• North America
• Europe
• Asia Pacific
• Latin America
• Middle East & Africa
North America mRNA Extraction and Purification Market, by Country, 2024-2031 (Value US$ Mn)
• U.S.
• Canada
Europe mRNA Extraction and Purification Market, by Country, 2024-2031 (Value US$ Mn)
• Germany
• France
• Italy
• Spain
• Russia
• Rest of Europe
Asia Pacific mRNA Extraction and Purification Market, by Country, 2024-2031 (Value US$ Mn)
• India
• China
• Japan
• South Korea
• Australia & New Zealand
Latin America mRNA Extraction and Purification Market, by Country, 2024-2031 (Value US$ Mn)
• Brazil
• Mexico
• Rest of Latin America
Middle East & Africa mRNA Extraction and Purification Market, by Country, 2024-2031 (Value US$ Mn)
• GCC Countries
• South Africa
• Rest of Middle East & Africa
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InsightAce Analytic is a market research and consulting firm that enables clients to make strategic decisions. Our qualitative and quantitative market intelligence solutions inform the need for market and competitive intelligence to expand businesses. We help clients gain a competitive advantage by identifying untapped markets, exploring new and competing technologies, segmenting potential markets, and repositioning products. Our expertise is in providing syndicated and custom market intelligence reports with an in-depth analysis with key market insights in a timely and cost-effective manner.
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