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In-Vitro Transcription Templates Market: Fueling Advances in RNA Research and Therapeutics

09-25-2024 09:09 AM CET | Health & Medicine

Press release from: InsightAce Analytic Pvt. Ltd

In-Vitro Transcription Templates Market: Fueling Advances

According to a new report by InsightAce Analytic, the "In-vitro Transcription Templates Market" in terms of revenue was estimated to be worth $ 277.5 million in 2023 and is poised to reach $ 1,134.1 million by 2031, growing at a CAGR of 19.5% from 2024 to 2031.

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Market Analysis:

The increasing demand for mRNA-based vaccines is driving revenue growth in the in vitro transcription template markets. In the upcoming years, developments in RNA technologies and the expanding trend of personalized medicine are also expected to drive market revenue growth.

Latest Drivers Restraint and Opportunities Market Snapshot:

Key factors influencing the global In-vitro Transcription Templates Market are:
• The augmentation of the biotechnology and pharmaceutical sectors fuels the demand for in-vitro transcription templates. These templates are essential for producing RNA molecules used in various applications such as gene therapy, drug discovery, and vaccine development.
• Continuous advancements in molecular biology techniques drive the demand for in-vitro transcription templates.
• The increasing interest in RNA-based therapeutics, including mRNA vaccines and RNA interference (RNAi) therapies, drives the demand for high-quality in-vitro transcription templates.

The following are the primary obstacles to the In-vitro Transcription Templates Market's expansion:
• Quality Control and Standardization are significant restraints. Ensuring the consistent quality and purity of in-vitro transcription templates can be challenging.
• The in-vitro transcription templates market is becoming increasingly competitive, with numerous companies and academic institutions offering similar products and services. Market fragmentation can make it challenging for customers to navigate and choose reliable suppliers.
• RNA molecules are inherently prone to degradation by RNases (ribonucleases). Maintaining RNA stability during template synthesis, purification, storage, and transportation is critical. Developing strategies to protect RNA integrity and prevent degradation throughout these processes presents a significant challenge.

Future expansion opportunities for the global In-vitro Transcription Templates Market include:
• The growing interest in RNA-based therapeutics, including mRNA vaccines, RNA interference (RNAi) therapies, and RNA-based gene therapies, presents significant opportunities for the in-vitro transcription templates market.
• The widespread adoption of CRISPR-based genome editing technology creates opportunities for the in-vitro transcription templates market. High-quality templates are essential for synthesizing guide RNAs (gRNAs) used in CRISPR-mediated genome editing experiments.
• Collaborating with academic and research institutions provides opportunities for companies to access cutting-edge technologies, expertise, and funding opportunities.

Key Industry Insights & Findings from the Report:

• The demand for customizable in-vitro transcription services and products is expected to drive the In-vitro Transcription Templates market's growth.
• The increasing interest in RNA-based therapeutics, including mRNA vaccines and RNA interference (RNAi) therapies, drives the industry's growth.
• Asia Pacific ruled the market and accounted for a revenue share of global revenue in 2023.
• One of the major concerns restraining industry growth is competition and market fragmentation.

List of Prominent Players in the In-vitro Transcription Templates Market:
• Thermo Fisher Scientific Inc.
• Qiagen N.V.
• Illumina Inc.
• Merck KGaA
• Bio-Rad Laboratories Inc.
• New England Biolabs Inc.
• Sigma-Aldrich Corporation
• Promega Corporation
• Life Technologies Corporation
• Roche Holding AG

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Recent Developments:
• In 2021, Thermo Fisher Scientific Inc. and PPD, Inc. had a deal worth $17.4 billion. This acquisition aims to strengthen Thermo Fisher's position in the life sciences market and expand its product offerings in clinical research.
• In Sept 2023, GenScript Biotech Corporation enhanced its IVT mRNA synthesis offerings by introducing personalized circular RNA (circRNA) and lipid nanoparticles (LNPs) formulation services. GenScript has promptly introduced new contract-manufactured reagent services as a demonstration of their dedication to offering state-of-the-art reagents that facilitate progress in areas such as vaccine development, protein replacement therapies, and gene and cell therapy.
• In 2019, Illumina Inc. had a deal with Pacific Biosciences of California, Inc., for $1.2 billion. This acquisition aims to expand Illumina's product offerings in the genomics market and enhance its capabilities in long-read sequencing.
• In September 2022, Thermo Fisher Scientific unveiled tailored Dynabeads technologies that facilitate the large-scale synthesis of mRNA. The Dynabeads™ Streptavidin for In Vitro Transcription & Dynabeads Carboxylic Acid for RNA Purification solutions

In-vitro Transcription Templates Market Dynamics:
Market Drivers: Pharmaceutical and biotechnology witness steady growth driver-
Pharmaceutical and biotechnology companies invest in research and development activities to introduce advanced treatments and therapies for various diseases. Organizations in the pharmaceutical and healthcare industries focus on template design and engineering, enhanced transcription efficiency, synthetic biology applications, high-throughput screening, RNA engineering and modification, and therapeutic applications to provide effective treatments for chronic diseases. Thus, the rise in investments in R&D in the healthcare and pharmaceutical sectors is contributing to the in-vitro transcription templates industry growth.

Challenges: High Cost Associated With Quality Control and Standardization:
Despite a diverse range of aesthetic applications, some limiting constraints are projected to hamper global market expansion over the forecast period. One of the key factors contributing to the global market's slowing growth is the high cost of these items. : Ensuring the consistent quality and purity of in-vitro transcription templates can be challenging. Variability in template quality may affect experimental results, leading to unreliable data. Establishing robust quality control measures and standardizing production processes are essential but can be complex and costly. Furthermore, because these items are not permanent, the individual may need to undergo recurring aesthetic treatments. As a result, the individual's financial load increases, and they may opt out of these elective procedures.

The Asia-Pacific Region is predicted for the largest CAGR During The Forecast Period.
The Asia-Pacific Region in the in Vitro Transcription Templates Market is likely to register a lead revenue share in the near future. This is due to the region's rising growth in research and development activities in the biotechnology and pharmaceutical industries. The region's ample number of biotech and pharmaceutical firms is a major factor for growth in in vitro transcription templates.

Segmentation of In-vitro Transcription Templates Market-
By Type
• Cancer
• Infectious Diseases
• Lifestyle Diseases
• Genetic Diseases
• Others

By Application
• Pharmaceutical & Biotechnology Companies
• CROs & CMOs
• Academics & Research
• Others

By Region-
North America-
• The US
• Canada
• Mexico

Europe-
• Germany
• The UK
• France
• Italy
• Spain
• Rest of Europe

Asia-Pacific-
• China
• Japan
• India
• South Korea
• South East Asia
• Rest of Asia Pacific

Latin America-
• Brazil
• Argentina
• Rest of Latin America

Middle East & Africa-
• GCC Countries
• South Africa
• Rest of Middle East and Africa

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InsightAce Analytic is a market research and consulting firm that enables clients to make strategic decisions. Our qualitative and quantitative market intelligence solutions inform the need for market and competitive intelligence to expand businesses. We help clients gain a competitive advantage by identifying untapped markets, exploring new and competing technologies, segmenting potential markets, and repositioning products. Our expertise is in providing syndicated and custom market intelligence reports with an in-depth analysis with key market insights in a timely and cost-effective manner.

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