Adrenal Crisis Market to Grow Positively at a Significant CAGR, asserts DelveInsight | Antares Pharma, Eton Pharmaceuticals, and others

DelveInsight's "Adrenal Crisis - Market Insight, Epidemiology and Market Forecast - 2034" report provides current treatment practices, emerging drugs, Adrenal Crisis market share of the individual therapies, current and forecasted Adrenal Crisis market size from 2020 to 2034 segmented by seven major markets. The report also offers current Adrenal Crisis therapy algorithms, market drivers, market barriers, and unmet medical needs to curate the best of the opportunities and assesses the underlying potential of the Adrenal Crisis market.
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Key highlights of the adrenal crisis market report:

Epidemiological growth factors for adrenal crisis include increased awareness, advancements in diagnosis, an aging population with chronic illnesses, rising medication usage, and improved access to healthcare. Understanding these factors is crucial for developing effective preventive measures and improving outcomes.
The acquisition of Antares Pharma by Halozyme has left the fate of ATRS-1902 uncertain, as no further updates on its development have been provided, though it remains in the company's pipeline.
Increased awareness of this unique histology has allowed the development of drugs that are specific to Adrenal Crisis and has begun to shed light on the similarities and possible unique aspects. These factors, along with the expected development and entry of emerging therapies, will boost the future market.
Adrenal Crisis market size in the seven major markets was USD 11.5 million in 2021.
The total number of prevalent cases of Adrenal Crisis in 7MM countries was 130,175 in 2021.
Obesity companies working in the market are Eton Pharmaceuticals, Antares Pharma and others

Adrenal Crisis Overview

Adrenal crisis, also known as adrenal insufficiency or Addisonian crisis, is a severe and potentially life-threatening condition that occurs when the adrenal glands fail to produce sufficient amounts of essential hormones, primarily cortisol and aldosterone. This can happen suddenly or may develop over time.

Key Features of Adrenal Crisis:

1. Rapid Onset: Symptoms can develop quickly and include severe fatigue, weakness, nausea, vomiting, and abdominal pain.

2. Hypotension: Low blood pressure (hypotension) is a hallmark of adrenal crisis, often leading to dizziness or fainting.

3. Dehydration: Due to the loss of aldosterone, which helps regulate fluid and electrolyte balance, dehydration is common.

4. Electrolyte Imbalances: Levels of sodium and potassium can become severely imbalanced, leading to further complications.

5. Hypoglycemia: Low blood sugar (hypoglycemia) can occur due to the lack of cortisol, which helps regulate glucose metabolism.

6. Fever and Weight Loss: These symptoms may also be present, along with a general sense of unease or feeling unwell.

Causes of Adrenal Crisis:

1. Autoimmune Disorders: The most common cause is an autoimmune disorder where the body's immune system attacks the adrenal glands (Addison's disease).

2. Infections: Severe infections can trigger an adrenal crisis, particularly in individuals with pre-existing adrenal insufficiency.

3. Trauma or Surgery: Physical trauma or surgery, especially if involving the adrenal glands, can lead to acute adrenal insufficiency.

4. Medication Withdrawal: Abrupt withdrawal of corticosteroid medications can precipitate an adrenal crisis in individuals who have become dependent on these drugs.

Diagnosis:

Diagnosis of adrenal crisis is based on clinical presentation and laboratory tests. Blood tests will typically show low levels of cortisol and aldosterone, along with electrolyte imbalances. Imaging studies, such as CT scans, may be used to assess the adrenal glands.

Treatment:

Immediate treatment is crucial and involves the administration of intravenous fluids to correct dehydration and electrolyte imbalances. Glucocorticoids (such as hydrocortisone) are given to replace the missing hormones. In severe cases, treatment may also include blood pressure support and management of any underlying infections.

Management and Prevention:

- Long-Term Hormone Replacement: Individuals with chronic adrenal insufficiency require lifelong hormone replacement therapy.

- Stress Dosing: During periods of increased stress, such as illness or surgery, individuals may need higher doses of glucocorticoids.

- Education: Patients and their families should be educated about the signs and symptoms of adrenal crisis and the importance of seeking immediate medical attention.

Adrenal crisis is a serious medical emergency that requires prompt diagnosis and treatment. With appropriate management, individuals with adrenal insufficiency can lead normal lives, but they must be vigilant about recognizing the signs of a crisis and seeking immediate medical care.
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Adrenal Crisis Epidemiological Insights
As per DelveInsight analysis, the total number of prevalent cases of Adrenal Crisis in 7MM countries was 130,175 in 2021.
Adrenal Crisis Treatment Market
The standard of care treatment for adrenal crisis involves an immediate infusion of hormone replacement drugs, including:

- Hydrocortisone: An initial bolus of 100 mg administered intravenously (IV) or intramuscularly (IM), followed by 200 mg over 24 hours or 50 mg IV or IM every 6 hours.
- 5% Dextrose Solution: For hypoglycemia.
- IV Sodium Chloride 0.9%: For hypovolemia.
- Antibiotics: If the patient shows persistent symptoms of infection.

The primary goal of these medications is to restore normal cortisol levels in the patient and stabilize their condition.

Promising Therapies in the Adrenal Crisis Pipeline
ATRS-1902
Zeneo
And others
Discover more about Adrenal Crisis therapies in the pipeline @ https://www.delveinsight.com/sample-request/adrenal-crisis-market?utm_source=openpr&utm_medium=pressrelease&utm_campaign=kpr

Leading Companies Working in the Adrenal Crisis Market
Antares Pharma
Eton Pharmaceuticals
And others
To understand key companies related to the Adrenal Crisis Market, get a snapshot of the Adrenal Crisis Regulatory and Patent Analysis @ https://www.delveinsight.com/sample-request/adrenal-crisis-market?utm_source=openpr&utm_medium=pressrelease&utm_campaign=kpr

Scope of the Adrenal Crisis Market Report
Study Period: 2020-2034
Coverage: 7MM [The United States, EU5 (Germany, France, Italy, Spain, and the United Kingdom), Japan]
Key Adrenal Crisis Companies: Antares Pharma, Eton Pharmaceuticals, and others
Key Adrenal Crisis Pipeline Therapies: ATRS-1902, Zeneo, and others
Therapeutic Assessment: Adrenal Crisis current marketed and emerging therapies
Adrenal Crisis Market Dynamics: Adrenal Crisis market drivers and barriers
Competitive Intelligence Analysis: SWOT analysis, PESTLE analysis, Porter's five forces, BCG Matrix, Market entry strategies
Unmet Needs, KOL's views, Analyst's views, Adrenal Crisis Market Access and Reimbursement
Table of Contents
1. Adrenal Crisis Market Key Insights
2. Adrenal Crisis Market Report Introduction
3. Adrenal Crisis Market Overview at a Glance
4. Adrenal Crisis Market Executive Summary
5. Disease Background and Overview
6. Adrenal Crisis Treatment and Management
7. Adrenal Crisis Epidemiology and Patient Population
8. Patient Journey
9. Adrenal Crisis Emerging Drugs
10. 7MM Adrenal Crisis Market Analysis
11. Adrenal Crisis Market Outlook
12. Potential of Current and Emerging Therapies
13. KOL Views
14. Adrenal Crisis Market Drivers
15. Adrenal Crisis Market Barriers
16. Unmet Needs
17. SWOT Analysis
18. Appendix
19. DelveInsight Capabilities
20. Disclaimer
21. About DelveInsight

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