Pancreatic Cancer Market to Progress at a CAGR of 7.3 % by 2032 | DelveInsight

DelveInsight's Pancreatic Cancer Market Insights report includes a comprehensive understanding of current treatment practices, pancreatic cancer emerging drugs, market share of individual therapies, and current and forecasted market size from 2019 to 2032, segmented into 7MM (the United States, the EU5 (the United Kingdom, Italy, Spain, France, and Germany), and Japan.

The pancreatic cancer market is anticipated to show positive growth, mainly attributed to the increasing incident cases and also, the launch of upcoming therapies during the forecast period. Moreover, the advances in disease mechanisms have yielded new diagnostic and therapeutic approaches, opening the way to more medicine development.

Key takeaways from Pancreatic Cancer Market Report
• As per DelveInsight analysis, the pancreatic cancer market size in the 7MM was approximately USD 1,649 million in 2021.
• As per the estimates, the total incident cases of pancreatic cancer were approx 175K in the 7MM in 2021.
• Leading pancreatic cancer companies such as AstraZeneca, Merck Sharp & Dohme LLC, Bayer, Roche, Celgene, Bristol Myers Squibb, BioLineRx, Alligator Bioscience, Bellicùm Pharmaceuticals, OSE Immunotherapeutics, Actuate Therapeutics, FibroGen, NeoImmuneTech, NOXXON Pharma, Silenseed Ltd., Amgen, NGM Biopharmaceuticals, Merus, Mirati Therapeutics, Rexahn Pharmaceuticals, Ocuphire Pharma, Processa Pharmaceuticals, ImmunityBio, Berg, Panbela Therapeutics, GlaxoSmithKline, Eleison Pharmaceuticals, Molecular Templates, Lokon Pharma AB, Cantargia AB, and others are developing novel pancreatic cancer drugs that can be available in the pancreatic cancer market in the upcoming years.
• The pancreatic cancer therapies in the pipeline include Motixafortide, Mitazalimab, BPX-601, Tedopi (OSE2101), AZD5305, Elraglusib (9 ING 41), NT-I7 (Efineptakin Alfa), Olaptesed pegol (NOX-A12), siG12D LODER, Sotorasib (LUMAKRAS/AMG 510), NGM120, Zenocutuzumab (Zeno, MCLA-128), Adagrasib (MRTX849), RX-3117, Anktiva (N-803), BPM31510 (ubidecarenone), Zejula (niraparib), Glufosfamide, LOAd703 (delolimogene mupadenorepvec), Pamrevlumab, GVAX Pancreatic Tumor Vaccine, and others.
• The pancreatic cancer market is expected to grow due to factors like an increase in the patient pool and the expected launch of novel emerging therapies.

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Pancreatic Cancer Overview
Pancreatic cancer develops in the tissues of the pancreas, an organ in the abdomen located behind the bottom portion of the stomach. The pancreas produces hormones that assist control blood sugar and release enzymes that promote digestion. Pancreatic cancer is a disorder in which malignant (cancer) cells originate in pancreatic tissues. The pancreas can grow in various ways, including malignant and noncancerous tumors. However, the exact pancreatic cancer causes are unknown. The average life expectancy of pancreatic cancer for individuals who are diagnosed before the tumor develops or spreads is 3 to 3.5 years.

Pancreatic Cancer Symptoms
Pancreatic cancer symptoms may include jaundice, dark urine, weight loss, and loss of appetite, weariness, and others. The pancreatic cancer diagnosis is difficult as the symptoms are frequently confused with those of other disorders, such as irritable bowel syndrome. Pancreatic cancer treatment options are determined by the degree of cancer. Options may include surgery, chemotherapy, radiation therapy, targeted therapy, or a combination of these.

Pancreatic Cancer Epidemiology Segmentation in the 7MM
• Total Pancreatic cancer Incident Cases
• Pancreatic cancer Molecular Alteration-specific Incident Cases
• Pancreatic cancer Stage-specific Incident Cases

Pancreatic Cancer Treatment Market
Surgical treatment is preferred for patients whose disease has been identified as localized or regional. Aside from surgery, chemotherapy is the most popular pharmaceutical pancreatic cancer treatment option. It is preferred for pancreatic cancer patients in all situations. Gemcitabine-based chemotherapeutic regimens are favored over 5-FU-based and other regimens in first-line therapy due to fewer side effects associated with gemcitabine compared to 5-FU-based treatment choices.
Gemcitabine + nab-paclitaxel can be used as second-line therapy for individuals who meet certain criteria and have had first-line FOLFIRINOX. In the second-line scenario, monotherapy with GEM or 5-FU is possible for patients with a somewhat low-performance status (ECOG 2), those with medical comorbidities, or elderly patients.

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Pancreatic Cancer Pipeline Therapies and Key Companies
• Motixafortide (BL-8040): BioLineRx/Merck Sharp & Dohme
• Mitazalimab (ADC-1013): Alligator Bioscience
• BPX-601: Bellicùm Pharmaceuticals
• Tedopi (OSE2101): OSE Immunotherapeutics
• AZD5305: Astra Zeneca
• Elraglusib (9 ING 41): Actuate Therapeutics
• Pamrevlumab (FG-3019): FibroGen
• NT-I7 (Efineptakin Alfa): NeoImmuneTech
• Olaptesed pegol (NOX-A12): NOXXON Pharma
• siG12D LODER: Silenseed Ltd
• Sotorasib (LUMAKRAS/AMG 510): Amgen
• NGM120: NGM Biopharmaceuticals
• Zenocutuzumab (Zeno, MCLA-128): Merus
• Adagrasib (MRTX849): Mirati Therapeutics
• RX-3117: Rexahn Pharmaceuticals/Ocuphire Pharma/Processa Pharmaceuticals
• Anktiva (N-803): ImmunityBio
• BPM31510 (ubidecarenone): Berg
• SBP-101: Panbela Therapeutics
• Zejula (niraparib): GlaxoSmithKline/Bristol Myers Squibb
• Glufosfamide: Eleison Pharmaceuticals/Molecular Templates
• LOAd703 (delolimogene mupadenorepvec): Lokon Pharma AB
• CAN04 (Nadunolimab): Cantargia AB
• GVAX Pancreatic Tumor Vaccine: Bristol-Myers Squibb, and several others

Pancreatic Cancer Market Dynamics
As the number of instances of pancreatic cancer rises, so does the pancreatic cancer market size, with the advent of genomic profiling technology and selective molecular targeted medicines, biomarkers have become increasingly significant in the clinical management of pancreatic cancer patients. Moreover, survival in pancreatic cancer patients is constantly improving, indicating that a better understanding of tumor pathobiology will lead to better therapies and outcomes in the pancreatic cancer market. Furthermore, due to a dearth of randomized neoadjuvant trials, research into the use of newer and more aggressive systemic regimens in the neoadjuvant setting to treat PDAC could potentially enhance outcomes in the pancreatic cancer market. Agents targeting the four most prevalent mutations in pancreatic cancer, KRAS, TP53, CDKN2A, and SMAD4, are still in clinical trials, and after the launch, they will change the pancreatic cancer market dynamics.

Pancreatic Cancer Market Growth Factors
However, several factors are limiting the growth of the pancreatic cancer market. PDAC is a complicated disease with high intra-tumoral heterogeneity and a thick, desmoplastic stroma that might restrict drug delivery to the tumor. Furthermore, it foreshadows an exceedingly intricate interplay of intercellular signals, making in vitro disease research difficult. Because of the genetic mutation diversity and dense connective tissue that forms the pancreas, PDAC is one of the most chemo-resistant types of cancer.

Scope of the Pancreatic Cancer Market Report
• Study Period: 2019-2032
• Coverage: 7MM [The United States, EU5 (Germany, France, Italy, Spain, and the United Kingdom), and Japan]
• Key Pancreatic Cancer Companies: AstraZeneca, Merck Sharp & Dohme LLC, Bayer, Roche, Celgene, Bristol Myers Squibb, BioLineRx, Alligator Bioscience, Bellicùm Pharmaceuticals, OSE Immunotherapeutics, Actuate Therapeutics, FibroGen, NeoImmuneTech, NOXXON Pharma, Silenseed Ltd., Amgen, NGM Biopharmaceuticals, Merus, Mirati Therapeutics, Rexahn Pharmaceuticals, Ocuphire Pharma, Processa Pharmaceuticals, ImmunityBio, Berg, Panbela Therapeutics, GlaxoSmithKline, Eleison Pharmaceuticals, Molecular Templates, Lokon Pharma AB, Cantargia AB, and others
• Key Pancreatic Cancer Therapies: Motixafortide, Mitazalimab, BPX-601, Tedopi (OSE2101), AZD5305, Elraglusib (9 ING 41), NT-I7 (Efineptakin Alfa), Olaptesed pegol (NOX-A12), siG12D LODER, Sotorasib (LUMAKRAS/AMG 510), NGM120, Zenocutuzumab (Zeno, MCLA-128), Adagrasib (MRTX849), RX-3117, Anktiva (N-803), BPM31510 (ubidecarenone), Zejula (niraparib), Glufosfamide, LOAd703 (delolimogene mupadenorepvec), GVAX Pancreatic Tumor Vaccine, and others
• Therapeutic Assessment: Pancreatic Cancer current marketed and emerging therapies
• Pancreatic Cancer Market Dynamics: Pancreatic Cancer market drivers and barriers
• Competitive Intelligence Analysis: SWOT analysis, PESTLE analysis, Porter's five forces, BCG Matrix, Market entry strategies
• Unmet Needs, KOL's views, Analyst's views, Pancreatic Cancer Market Access and Reimbursement

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Table of content
1. Key Insights
2. Report Introduction
3. Pancreatic Cancer-Market Overview at a Glance
4. Pancreatic Cancer - Future Prospects
5. Executive Summary of Pancreatic Cancer
6. Key Events
7. Disease Background and Overview
8. Treatment and Management
9. Methodology
10. Epidemiology and Patient Population
13. Emerging Therapies
14. Pancreatic Cancer: Seven Major Market Analysis
15. Market Access and Reimbursement
16. KOL Views
17. SWOT Analysis
18. Unmet Needs
19. Appendix
20. DelveInsight Capabilities
21. Disclaimer
22. About DelveInsight

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